Tag: genetics

November 2016 Writing for Children’s Hospital of Philadelphia

I wrote the following articles published in November 2016 by the Children’s Hospital of Philadelphia Research Institute:

Linking Patients and Data, Medicine and Science: CAVATICA Data Analysis Platform Launches

Untangling Attention Difficulties in Autism

Smart Robotic Toy Gym Could Identify Early Signs of Babies’ Developmental Delay

Cellular Energy Flaws Studied as Contributor to Schizophrenia

A ‘Critical Mass’ of Mitochondrial Disease Research Accelerates Treatment Quest

CHOP Research In the News: Body and Mind, Stayin’ Alive, ADHD Guidelines, Innovation Leadership

Q&A: How Pediatricians Can Help Suburban Families in Poverty

CHOP Research In the News: From Good Starts to Young Adult Transitions

CHOP Honors Superhuman Abilities of Clinical Research Coordinators

October 2016 Writing for Children’s Hospital of Philadelphia

I wrote (or edited, as noted) the following articles published in October 2016 by the Children’s Hospital of Philadelphia Research Institute:

Scientists Seek Mitochondrial Mechanism to Overcome Cancer Treatment Resistance

Finding of Variability in Antibiotic Prescribing Yields Improvements, Accolades

Project Aims to Automate Adverse Event Reporting in Cancer Clinical Trials

In a Teenager’s Brain, HIV Infection Could Cause Unique Damage

How to Address Four Factors That Limit Gender Equality in Academic Medicine

I noticed a CHOP-affiliated co-author, Dr. Ganetzky, listed on a piece in the journal Academic Medicine calling for action on gender equality. I approached Dr. Ganetzky with the idea for a guest blog post on the subject and worked with her to refine and edit the post for publication.

CHOP Research In the News: Ear Infection Genetics, Childhood Cancer Heredity, Vaccine Anniversary

CHOP, Penn Researchers Share Progress and Tips for Using mHealth Tools

CHOP Research In the News: Cancer Moonshot Yields Data-Sharing Initiatives, Hemophilia Surprise, Mitochondrial Medal

Mentorship in Medicine, Zebras, and Holsteins: Q&A with Elaine Zackai

September 2016 Writing for The Children’s Hospital of Philadelphia

I wrote the following stories published by The Children’s Hospital of Philadelphia Research Institute in September 2016:

Going with the Flow: How Lymphatics is Emerging as Medicine’s Newest Specialty

Pediatricians May Better Help Parents Quit Smoking With Decision Support Tool

Discovering How a Neurological ‘Pit Crew’ Keeps the Brain on Track

Scientists Identify Molecule Controlling Inflammatory Immune Response

Neuroblastoma Drug Candidates Target Key Henchmen of a Supervillain Oncogene

Fresh Hope for Treating a Rare Progressive, Lysosomal Storage Childhood Disease

CHOP Research In the News: Cancer Moonshot, Why Children Get Cancer, and a Push for Vaccination

Patients as Partners and the Legacy of Henrietta Lacks: A Q&A with David Lacks

Do Food Allergies Increase the Risk of Asthma? Key Questions From a New Study

CHOP Research In the News: Emmy Award, Kids and the Cancer Moonshot, Precision Approach to Epilepsy, Concussion Monitoring App

May 2016 Writing for The Children’s Hospital of Philadelphia

I wrote the following stories published by The Children’s Hospital of Philadelphia Research Institute in May 2016:

Studies Support Parent-Teen Communication to Improve Adolescent Health

Mitochondrial Medicine Pioneer Inducted to Italian Academy of Sciences

Seeking Serotonin-Connected Solutions to Heart Valve Disease

Collaborations on Language-Focused Autism Research Gain Momentum

Using Sociology to Outsmart Superbugs

CHOP Research In the News: Regulating Iron, Mother’s Dedication, Knee Troubles

CHOP Research In the News: Summer-Ready Stories about Families, Travel, and Science

April 2016 Writing for The Children’s Hospital of Philadelphia

I wrote the following articles published by The Children’s Hospital of Philadelphia Research Institute in April 2016:

Restoring Balance in the Brain After Concussion

CHOP Oncologist Appointed to Blue Ribbon Panel for National Cancer Moonshot

Teaching a Computer to See Like a Dermatologist

Study Maps Early Connectivity Networks in Newborn Babies’ Brains

CHOP Research In the News: Transgender Youth, Vaccines, and Sleep

In Bench to Bedside: Finding Research Success in Setbacks

Growing Into Healthy Relationships: A Teen Dating Violence Q&A

CHOP Research In the News: Genetic Superheroes, Excess Bone, and Secondhand Smoke

Coordinating Research with 80 Million Participants: A PCORnet Q&A

Hakon Hakonarson Honored for Excellence in Research Mentoring

CHOP Research In the News: Plastic Bronchitis, Baby BMI, Voice at the Vatican

March 2016 Writing for The Children’s Hospital of Philadelphia

I wrote the following stories published by The Children’s Hospital of Philadelphia Research Institute in March 2016, except as otherwise indicated:

CPR for Children Gets Smarter

In this story, I explored a body of research on improvements to in-hospital CPR that CHOP clinician-researchers had been at work on for more than a decade, but that had been under-reported within the CHOP community. Coincidentally, I discovered the story just as the investigators were preparing to be awarded a major NIH grant that put several pieces of their program’s work together, so I was able to announce the grant through this feature article.

Seeing the Impact of a Decade of Genomics Discoveries

This story looks back on the first decade of accomplishments of a center that was established as one of the largest research investments at CHOP at the time. I pursued the story initially due to Dr. Hakonarson’s recognition on the Thomson Reuters “highly cited” list but broadened its focus once I realized that his center’s tenth anniversary was approaching.

A Molecular Balancing Act to Fight Autoimmune Disease and Cancer

I found out about one new grant Dr. Hancock had received. To my surprise, when I met with him for an interview, he mentioned that he had received notice on the same day of another award to study the same molecules but for an opposite effect. It was completely fascinating! This molecular biology story turned out to be one of the most popular articles in our Bench to Bedside publication that month, despite the relative obscurity of its focus.

Concussions’ Unpredictability Underscores Need for Follow-Up Care

Using Doctors’ Certification Requirements to Increase HPV Vaccination

CHOP Honors Distinguished Research Trainees on Poster Day

CHOP Research In the News: DNA Scrunching, Video Games, Smart Drugs

CHOP Research In the News: Obesity, PTSD, and Alice in Wonderland

Staying Safe in the Sun: A Sun Protection Q&A

CHOP’s Foerderer Awards Support Novel Biomedical Research Studies

A Week in the Life of the Research Navigator

For this guest blog post written by Katherine Yang-Iott, I initially proposed the concept of hosting a blog post about Katherine’s new role, approached Katherine, and worked with her to develop a “day in the life” concept into a “week in the life” post. My role included guiding her in how to think about writing the piece through contributing multiple phases of editing to shape the final product.

Discovery Unites Three Families with Rare Syndrome

Originally published in the 2015 CHOP Research Annual Report.

I wrote this article based on a new interview with a parent and a past press release and blog post.

Excerpt:

When they met as a group for the first time, Leta, Liam, and Nadira seemed to bond instantly. All three are under 4 feet tall, have similar mannerisms, wide-set eyes, and bubbly personalities. They live with chronic respiratory problems and other medical challenges, in addition to cognitive and physical developmental delays.

“They look more like siblings than their actual blood siblings,” said Melissa Ashton-Grant, mother of Nadira. “To see how they interacted with each other, it felt right.”

The children’s similarity was no coincidence — and confirming and understanding their connection was no small matter. The three families gathered in March to celebrate because researchers at The Children’s Hospital of Philadelphia had discovered the rare genetic mutation their children share, and had given their cryptic constellation of symptoms a name: CHOPS Syndrome. CHOPS is an acronym that stands for Cognitive impairment and coarse facial features, Heart defects, Obesity, Pulmonary involvement, Short stature and skeletal dysplasia (abnormal bone development).